Address of main study secretariat: Evy Nilsson, Ingrid Dahlberg and Dr. Thor Alvegaard, Regional Tumor Register, University Hospital of Lund, SE-221 85 Lund, Sweden Tel. + 46-46-177555 Fax. + 46-46-188143 A register of ISG patients will be kept at Istituto Ortopedico Rizzoli, Via Pupilli 1, IT-40136 Bologna, Italy. All the Italian patients will be registered in the ISG register and its data will be sent to the main study secretariat in Sweden. Tel. + 39-051-6366829 Dr. Bacci ; , + 39-051-6366759 Dr. Picci ; Fax. + 39-051-6366277 Dr. Bacci ; , + 39-051-584422 Dr. Picci.
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Lichen planus is not necessarily a manifestation of chronic renal failure, but has been considered an extrahepatic manifestation of HCV. HCV in ESRD has been reported to be as low as 8% and as high as 51%, thus having clinical significance by virtue of its prevalence Zacks & Fried, 2001 ; . Skin lesions of lichen planus can be disfiguring with the description of the six "Ps" used in diagnosis: pruritic, polygonal, planar flat-topped ; , purple papules, and plaques Katta, 2000 ; . Some patients remain asymptomatic with the eruptions while others complain of severe pruritus. Figure 6 demonstrates a cutaneous lichen planus on the lower extremity, but it can involve the oral mucosa, nails, scalp, or genital mucosa as well. Even though there has been a demonstrated association between HCV and occurrence of lichen planus, most cases are idiopathic. Certain medications have also been linked with development including gold, antimalarial agents, penicillamine, thiazide diuretics, beta blockers, nonsteroidal anti-inflammatory drugs, quinidine, and angiotensin-converting enzyme inhibitors. In a case report by AlKhenaizan 2001 ; , a case of lichen planus occurred following administration of hepatitis B vaccine. Although rare, hepatitis B vaccination has been reported on more than one occasion to precipitate a lichen planus eruption both oral and cutaneous ; . Lesions tend to develop after a 3-day to 3-month latency period between injection and presentation. Diagnosis is confirmed with punch biopsy and histopathology, for example, proscar for bph.
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Any Chicago-area physicians overlook outstanding local publications as they search for progress elsewhere. In Clinical Laboratory Medicine, Dr. McClatchy, the late head of pathology at Loyola, provides an example of such local publications. This work warrants the attention of all members, not only out of local pride, but also as a way to update laboratory diagnostic procedures with the help of new innovations. Molecular pathology, thoroughly explored by Dr. Serhan Aikan, also from Loyola, has come to the forefront, providing a fundamental basis for the general laboratory, clinical chemistry, medical microbiology, cytogenetics, histocompatibility, immunopathology, microbiology, coagulation, and hematology. Blood bank and transfusion medicine is well-covered by Dr. Harold A. Oberman from the University of Michigan. From beginning to end, this book is devoted to providing the reader with the latest clinical laboratory medicine, well organized and thoroughly illustrated. It also adequately acknowledges the work of professionals throughout the world who have devoted their lives to bettering patient care by constantly improving the art and science of clinical laboratory medicine . William H. Wehrmacher, MD.
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