4.3. UNIFICATION P1 1 P0 ; This entails that P1 is a valid, well-typed proof problem. Proof: Induction on the structure of the derivation of the unification judgement. The condition 1 t1 ; 1 resp. 1 t1 ; 1 immediately verified by inspection of the rules. The fact that P1 1 P0 ; also established by a simple inductive argument, observing the following 'transitivity' in rules MV-term ; , app-app ; etc.: if P1 1 and P2 2 P1 ; , then P2 1 2 ; show that 1 is a valid, well-typed instantiation for P0 , we only consider the rule MV-term ; . For the other rules, the claim follows from the induction hypothesis. The following conditions have to be verified in order to show that the resulting instantiation is valid and well-typed: The unification problem in the precondition of the rule has to be valid in the sense that both typeP0 ?n ; and T are well-typed in context ctxtP0 ?n ; . Since P0 is a valid proof problem and ?n P0 , we have that typeP0 ?n ; is well-typed in ctxtP0 ?n ; . The fact that T is well-typed in ctxtP0 ?n ; is enforced by the first premiss of rule MV-term ; . The resulting instantiation in particular the assignment of 1 t ; must be well-typed. If P0 ; T typeP0 ?n ; P1 ; 1 , can conclude by induction hypothesis that 1 T ; 1 type ?n . The fact that 1 is a well-typed instantiation permits to show cf. Proposition 2.72 ; that 1 ctxt ?n 1 t ; and thus, by cumulativity, that 1 ctxt ?n 1 t ; type ?n . Therefore, ?n : 1 t ; typecorrect assignment. The validity of the resulting instantiation has to be ensured. This follows immediately from the definition of the predicate valid . The instantiation 1 is defined in the sense of Definition 2.65 ; : By the precondition ?k MVars T ; .?k P0 ?n, dom 1 ; only contains metavariables ?k P0 ?n, thus dom 1 ; ? and by the definition of instantiation, for all ?m MVars 1 t , 1.
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LIPID-REGULATING CARDIOVASCULAR MULTITHERAPY FIXED I2005 COMBINATION PRODUCTS Includes products which are indicated for cardiovascular lipid disorders together with at least one other cardiovascular condition, eg hypertension. These products contain two or more active substances together in a single dosage form, eg a single tablet, capsule, etc and aciphex.
Vitamins capsules.96 Voriconazole.62 Warfarin.30 Welldorm.40 Xylometazoline .109 Zalcitabine .63 Zanamivir.65 Zidovudine.63 Zinc sulphate .95, 120 Zineryt .115 Zoledronic acid .74 Zolmitriptan.50 Zonisamide.51 Zuclopenthixol .42 Zuclopenthixol decanoate.42 Zbyan . See buproprion.
Likewise the globalization of the pharmaceutical industry has lead to its growth from a few hundred companies in the US during the 1980's, to almost 1, 500 companies in the US and close to 3, 000 companies outside of the US currently, according to Ernst & Young's "Beyond Borders : Global Biotechnology Report 2005" These two trends together have created a unique alternative business model to the FIPCO. As Big Pharma companies have merged, key assets of acquired companies have often been sold or phase-out including surplus of R&D centers, Manufacturing plants, Chemical synthesis and actos.
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