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Alternative agents include terbinafine hydrochloride lamisil ; , fluconazole diflucan ; , and itraconazole sporanox ; dr berg is a resident physician and dr erickson is a faculty physician, department of family practice, hennepin county medical center, minneapolis. Especially important to take whenever you're on sporanox or diflucan.

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Fetuses were several magnitudes lower than for their mothers p 0.003 and 0.013 for peak levels and AUC, respectively; Fig. 1; Table 1 ; . However, these parameters in the plasma of the fetuses chronically exposed to cocaine were nearly twice as large as in the fetuses subjected to only a single cocaine treatment p 0.039 and 0.047 for peak levels and AUC, respectively; Table 1 ; . We detected no significant differences between chronically treated mothers and fetuses in the values of t1 2, Kel, and MRT for cocaine p 0.05; Table 1 ; . These values were also similar to those in the animals receiving a single oral administration of the drug p 0.05; Table 1 ; . In both chronically treated mothers and fetuses, the levels of cocaine in the circulation declined to undetectable levels by 8 h following administration. Similar to those for cocaine, the peak levels and daily AUC of benzoylecgonine in the chronically exposed fetuses were several magnitudes lower than those in their mothers p 0.002 for both peak levels and AUC; Fig. 1; Table 1 ; . In addition, the peak levels and AUC of benzoylecgonine in the orally chronically treated pregnant monkeys were not significantly different from the ones in the animals receiving a single oral dose of cocaine p 0.05; Fig. 1; Table 2 ; . However, both of these parameters were significantly larger in the fetuses of the former monkeys than in the fetuses of the latter animals p 0.038 and 0.045 for peak levels and AUC, respectively; Fig. 1; Table 2 ; . There were no significant differences between chronically treated mothers and fetuses in the values of t1 2, Kel, and.

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1. Department of Neurology, Sina hospital, Tehran university of medical sciences, Tehran, Iran. 2- School of Health, Tehran University of Medical Sciences, Tehran, Iran.
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