Other: 76161070 76161090 76169100 Having shanks, threads or holes over 6 mm in diameter Other -Other: --Cloth, grill, netting and fencing, of aluminum wire --Other: Luggage frames Other Unwrought lead: -Refined lead -Other: --Containing by weight antimony as the principal other element --Other: Lead bullion Other Lead waste and scrap Lead bars, rods, profiles and wire Lead plates, sheets, strip and foil; lead powders and flakes: -Plates, sheets, strip and foil: --Sheets, strip and foil of a thickness excluding any backing ; not exceeding 0.2 mm --Other -Powders and flakes Lead tubes, pipes and tube or pipe fittings for example, couplings, elbows, sleeves ; Other articles of lead Unwrought zinc: -Zinc, not alloyed: --Containing by weight 99.99 percent or more of zinc --Containing by weight less than 99.99 percent of zinc: Casting-grade zinc Other -Zinc alloys Zinc waste and scrap Zinc dust, powders and flakes: -Zinc dust -Other: --Powders --Other Zinc bars, rods, profiles and wire Zinc plates, sheets, strip and foil Zinc tubes, pipes and tube or pipe fittings for example, couplings, elbows, sleeves ; Other articles of zinc: -Articles of a type used for household, table or kitchen use; toilet and sanitary wares; all the foregoing and parts thereof of zinc -Other 2.2% 3% Free 20% 3% A A E A 5.5% 6% 2.5% Free 2.5% on the value of the lead content 2.5% on the value of the lead content 2.5% on the value of the lead content 2.5% on the value of the lead content Free 1.2% B B A E.
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Fda based its conclusions on two clinical trials - one in the united states and one in europe - that compared prograf with cyclosporine-based treatments for liver transplants.
The authors acknowledge the Center for Computational Sciences at the University of Kentucky for supercomputing time on Superdome a sharedmemory supercomputer, with 4 nodes and 256 processors ; . The research was supported by National Institutes of Health National Institute on Drug Abuse grant R01DA013930 to C.-G. Zhan.
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The summary of product ch aracteristics spcs ; for prograf site ; indicates that tacrolimus is extensively metabolised by the hepatic microsomal cytochrome p-450 isoenzyme, cyp3a drugs, which inhibit or induce cyp3a enzymes may, therefore, affect metabolism of tacrolimus and increase or reduce blood levels.
Advertised before acceptance under section 20 ; 1 proviso 1309690 - September 17, 2004 LAUREUS WORLD SPORTS AWARDS LTD., A COMPANY ORGANISED, REGISTERED AND EXISTING UNDER THE LAWS OF UNITED KINGDOM ; , 15 HILL STREET, LONDON, W1J 5 QT, UNITED KINGDOM. MANUFACTURER, TRADER AND SERVICE PROVIDER, Address for service in India Agents address: ANAND AND ANAND. B - 41, NIZAMUDDIN EAST, NEW DELHI - 110 013. Proposed to be used. DELHI ; CL. 36 CHARITABLE FUND RAISING INCLUDING CHARITABLE COLLECTIONS, MANAGEMENT AND MONITORING OF CHARITABLE FUNDS, TRUSTEE SERVICES, PROVISION OF INFORMATION AND ADVICE RELATING TO THE AFORESAID SERVICES INCLUDED IN CLASS 36. CL. 41 ENTERTAINMENT AND EDUCATIONAL SERVICES, ARRANGING AND CONDUCTING SPORTING EVENTS AND ATHLETIC COMPETITIONS, ARRANGING AND CONDUCTING AN AWARDS PROGRAM AND CEREMONIES, EDUCATION SERVICES, INCLUDING PROVIDING INCENTIVES TO PEOPLE AND ORGANISATIONS TO DEMONSTRATE EXCELLENCE IN THE FIELD OF SPORTS AND ATHLETICS THROUGH THE ISSUANCE OF AWARDS, TELEVISION AND RADIO PROGRAMS FEATURING SPORTING EVENTS, SPORTS AND ATHLETIC COMPETITIONS, AWARDS SHOWS, THE HISTORY OF SPORTS AND ATHLETICS, HISTORICAL FIGURES AND FAMOUS PERSONS IN THE ATHLETIC AND SPORTING FIELDS, ARRANGING AND CONDUCTING EXHIBITIONS IN THE FIELDS OF SPORTS AND ATHLETICS, PROVIDING FACILITIES FOR SPORTS AND ATHLETIC EVENTS, COMPETITIONS AND AWARDS, PROVIDING SPORTS INFORMATION BY MEANS OF TELEPHONE AND A WEB SITE VIA A GLOBAL COMPUTER NETWORK, MUSEUMS, PROVIDING FACILITIES FOR SPORTS TOURNAMENTS, PROVIDING VARIOUS FACILITIES FOR AN ARRAY OF SPORTING EVENTS, SPORTS AND ATHLETIC COMPETITIONS AND AWARDS PROGRAMS; PROVIDING INFORMATION ON HISTORICAL AND CURRENT SPORTS AND ATHLETIC FIGURES, THE HISTORY OF SPORTS, A SPORTS AWARD PROGRAM, VARIOUS SPORTING AND ATHLETIC EVENTS VIA A WEB SITE BY MEANS OF A GLOBAL COMPUTER NETWORK INCLUDED IN CLASS 41 and
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FOR IMMEDIATE RELEASE -- Gardena, CA -- May 11, 2006 -- Spectrum Laboratory Products, Inc, Spectrum ; , Gardena, California, is initiating a voluntary nationwide recall of the active pharmaceutical ingredient API ; tacrolimus after learning some lots are subpotent. Tacrolimus is an immunosuppressive drug used to prevent rejection of transplanted solid organs such as heart or kidney. Blood levels of tacrolimus in some patients were significantly lower than would be expected based solely on the lower assay results. The use of sub-potent tacrolimus in compounded drugs for transplant recipients may lead to sub-therapeutic tacrolimus blood levels and an unacceptably increased risk of solid organ transplant rejection. At least one injury has been reported. FDA has been apprised of this action. Tacrolimus is identified as Catalog Number T3192. Recalled lots include the following: TA1210, UD1060, UF0298, UL0964, VB0031. Spectrum tacrolimus API has been used by pharmacies for compounding purposes. Patients receiving tacrolimus for solid organ transplant should not stop taking their medication, but rather should check with their physician or pharmacist. This recall does not apply to tacrolimus marketed in finished dosage form as 0rograf Astellas Pharma, US ; or to Progdaf oral capsules that have been used for compounding.
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P. Ulrich, G. Paul, E. Perentes, A. Mahl, D. Roman. Novartis Pharma AG, Basel, Switzerland Assessment of the immune system's capability to respond to antigens with the generation of specific antibodies, whilst under the influence of a test article, is required in toxicity tests according to the European guideline for repeated dose toxicity testing of medicinal products. The purpose of this study in rats was to validate methodology for the determination of Keyhole Limpet Hemocyanin KLH ; -specific antibodies under the influence of an immunologically active compound. The immunosuppressant FK506, commercially available as Prograf, was administered orally gavage ; to 5 rats sex group at dosages of 0.5 or 3 mg kg day, once daily for a period of 4 weeks. On days 14 and 22, KLH was administered subcutaneously, with an adjuvant AluGel ; , to the two treated groups and a control i.e. without FK506 treatment ; approximately 1 hour following administration of FK506. Terminal investigations included haematology parameters, titration of KLH-specific antibodies in serum ELISA ; , macroscopic pathology, spleen and thymus weights, immunophenotyping of splenocytes FACS analysis ; and histopathology of the lymphatic tissues. At 3 mg kg day a minimal reduction of subcutaneous KLH-induced granuloma formation and a moderate to marked reduction of germinal centre development axillary lymph node and spleen ; were observed. Reduced CD4 + T-cell ; counts were found in the spleen of males, consistent with a suppressed production of KLH-specific antibodies IgG in both sexes, IgM in males only ; and a higher incidence of atrophy in the periarteriolar lymphoid sheaths of males. Slight to moderate lymphopenia was present in both sexes at 3 mg kg day. These findings are consistent with the known pharmacological activity of FK506. In conclusion, determination of antibody titres following immunisation of rats with KLH, with concurrent exposure to a test item, appears to be a valid method in the context of the immunotoxicity evaluation required by European regulation and
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Use among IDUs has increased to over 90% when visiting commercial sex workers CSW ; . The prevalence of HIV in IDUs was low. In contrast, HBV prevalence was 18%. HCV prevalence increased from 7% in 1997 to 66% in 2002 and 80% in 2003. The prevalence of HIV and HBV in commercial sex workers CSWs ; was 9% each. Most CSWs entertained 3-4 clients a day and most of them used condoms. Thirty six cases were found to be having active tuberculosis. NICED has liased with the state health services and arranged for their treatment under RNTCP. Impact of Counselling on Coping Behaviour of HIV Positive Cases in Different States Counselling with HIV positive cases aims to enhance the medical, social and emotional management of the condition by way of strengthening coping mechanisms of the individuals. In order to look into the quality of counselling and its impact on the coping behaviour of HIV infected people, study was carried out at Delhi, Mumbai, Channai and Ranchi. At each centre about 200 HIV positive and 200 control cases and 50 counsellors have been studied by using standard psychological tools for anxiety, depression and coping behaviour and structured questionnaires. The data of the study is being analyzed and pentoxifylline.
Continued ; was not relied upon by the court as evidence of the convictions. Moreover, a presentence report is not sufficient to establish prior convictions for sentence enhancement. See State v. Richards, 166 Ariz. 576, 579, 804 P.2d 109, 112 App. 1990 ; presentence report insufficient to prove prior convictions for enhancement ; . See also State v. Hurley, 154 Ariz. 124, 132, 741 P.2d 257, 265 1987 State v. Hauss, 140 Ariz. 230, 231, 681 P.2d 382, 383 1984 ; discussing proof required to establish prior convictions ; . Because the court's error resulted in sentence enhancement, it constitutes fundamental error. See State v. Thues, 203 Ariz. 339, 340, 4, P.3d 368, 369 App. 2002 ; . We review for fundamental error even when defense counsel assented to the challenged actions of the court. State v. Stuart, 168 Ariz. 83, 87, 811 P.2d 335, 339 App. 1990 ; reviewing for fundamental error when judge, with defense counsel's consent, instructed jury foreman to modify verdict ; . It is therefore immaterial that defense counsel agreed with, rather than objected to, the court's inaccurate account of the stipulation. 6.
Point trials are valuable in confirming the hypothesis that lowering LDL-C with drugs is beneficial. However, these same trials are not very useful concerning decisions about product selection or treatment approaches from the perspective of an institution or an individual practitioner. Our study was designed to assess the direct costs of treating patients with hypercholesterolemia using three common and trental.
The allergen extract CS-560 ; used in the present study was made by the conjugation of pullulan a-1, 4-a-1, 6-glucan ; , a neutral polysaccharide, with Cry j 1 and 2 purified allergenic substances from Japanese cedar pollen ; , by the collaboration of Hayashibara Biochemical Institute Tokyo, Japan ; and Sankyo Pharmaceutical Co. Tokyo, Japan ; and is characterized by weak allergenicity, but strong antigenicity, having an immunologic profile of allergen and stable antigen titre. This extract is supplied as a solution of 200 ng CS-560 Cry j1 : Cry j2 4.1 ; and 0.3 mg human serum albumin mL solution.
Or click the first letter of a drug name: a b c advanced search drugs & medications diseases & conditions pharmaceutical news & articles pill identifier drug interactions checker medical encyclopedia medical dictionary community forums welcome guest register or sign in my viewing history my drug list my interactions lists member offers consumer drug information medfacts peograf prgraf generic name: tacrolimus injection ta-kroe-li-mus ; brand name: prograt prograf may leave you less able to fight infection and could also cause lymphoma and pheniramine.
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As budget proceedings for fy 1993 began, fda commissioner david kessler testified before congress that the user fee issue was aspirin: a new look at an old drug scientists continue to investigate what seem to be an unending number of possible new uses for the world's most widely used drug and progesterone.
Medicines. An interesting example is the potential interaction between thyroxine and celery seed tablets. Case reports Our first case involved a 55-year-old woman who, after considerable monitoring, had finally been stabilised on a daily dose of thyroxine 100 microgram. A month later, her doctor found that her T4 levels were low again and her dose was doubled. The patient then remembered that in the past month she had also started taking celery seed tablets for osteoarthritis. Suspecting a potential interaction, she ceased the celery seed tablets without increasing the thyroxine dose as the doctor had advised. Next time her thyroxine levels were checked they had increased to within the normal range. She tried recommencing celery seed a month later but after a week she felt lethargic, bloated and had dry skin. When she stopped the celery seed tablets, she reported that her `general energy levels improved'. A second report was received from a 49-year-old woman who had taken thyroxine for many years. When her T4 became extremely low her doctor suspected that she had not been taking her tablets. The patient argued that she had taken her thyroxine, but she had recently commenced taking celery seed tablets to treat arthritis. She ceased the celery seed tablets and one month later her thyroxine levels had returned to within the normal range. Evidence Celery seed extracts Apium graveolens ; are a popular herbal remedy for the treatment of arthritis, gout, fluid retention and cystitis. Celery seed fruit should not be confused with the edible celery stem.1 Studies have shown that celery plant extracts have anti-inflammatory activity against carrageenaninduced rat paw oedema.2 Hypotensive and hypoglycemic activities have also been reported.1 In preliminary research, five of 23 celery-based preparations showed antiarthritic, for example, prograf 2 mg.
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Drugs currently being considered by the SMC SMC and NICE new drug appraisals process Survey of non-formulary PPI prescribing SMC new drug recommendations for drugs considered in December 06 Drugs currently being considered by the SMC with advice due on 12 February 2007: SMC Submission 341 07 Rimonabant 20mg tablet Acomplia ; 342 07 Pemetrexed 500mg injection Alimta ; 343 07 Sunitinib 50mg capsules Sutent ; 344 07 TachoSil medicated sponge 345 07 Interferon beta-1b 250microgram ml for solution for injection Betaferon 346 07 Tacrolimus 5mg ml concentrate for infusion and 0.5, 1mg, 5mg hard capsules Orograf ; 347 07 Deferasirox dispersible tablets Exjade ; 340 07 Propiverine 30mg m r capsule Detrunorm XL ; Indication Treatment of obesity Locally advanced or metastatic nonsmall cell lung cancer Advanced and or metastatic renal cell carcinoma Use during surgery for improved haemostasis Treatment of patients with a single demyelinating event. Prophylaxis of transplant rejection in heart allograft recipients Chronic iron overload Urinary incontinence, urgency and frequency and
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Both treatments in this study contain a new formulation of tacrolimus generic name for prograf ; , and as a result, patients participating will take mr tacrolimus once every day.
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Drug Req. Drug Name Tier Limits IMMUNOSUPPRESSANT DRUGS Generics azathioprine 1 PA cyclosporine 1 PA gengraf 1 PA Brands CELLCEPT 2 PA PROGRAF 2 PA RAPAMUNE 2 PA MISCELLANEOUS ANTINEOPLASTIC DRUGS Generics etoposide 1 hydroxyurea 1 Brands DROXIA 2 EMCYT 2 GLEEVEC 2 QL HEXALEN 2 VESANOID 2 and
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The average price of a prescription drug at the retail level increased 10.1% from 2000 to 2001, from $45.27 to $49.84. This percentage increase includes manufacturer price increase, the distributor's mark up and the mark up by the retail store, as well as the shift to higher cost drugs. ; Tables 1 and 3 ; A rise in the price of drugs accounted for 37% of the growth in drug spending in 2001. A shift to the use of newer, more costly drugs accounted for 24% of the rise in drug spending in 2001. Figure 4.
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It is recommended that patients initiate oral therapy with Pr9graf capsules if possible. If IV therapy is necessary, conversion from IV to oral Proyraf is recommended as soon as oral therapy can be tolerated. This usually occurs within 2-3 days. The initial dose of Prograf should be administered no sooner than 6 hours after transplantation. In a patient receiving an IV infusion, the first dose of oral therapy should be given 8-12 hours after discontinuing the IV infusion. The recommended starting oral dose of Prograf capsules is 0.10-0.15 mg kg day administered in two divided daily doses every 12 hours. Co-administered grapefruit juice has been reported to increase tacrolimus blood trough concentrations in liver transplant patients. See Drugs that May Alter Tacrolimus Concentrations ; . Dosing should be titrated based on clinical assessments of rejection and tolerability. Lower Prograf dosages may be sufficient as maintenance therapy. Adjunct therapy with adrenal corticosteroids is recommended early post transplant. Dosage and typical tacrolimus whole blood trough concentrations are shown in the table above; blood concentration details are described in Blood Concentration Monitoring: Liver Transplantation below.
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Restricted use: tacrolimus Prograf ; is accepted for restricted use within NHS Scotland for the prophylaxis of transplant rejection in heart allograft recipients. It has shown comparable efficacy to ciclosporin-based regimens in prevention of acute rejection. It is restricted to use in patients where ciclosporin is not suitable and
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