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Prices for most new patented drugs are limited such that the cost of therapy for the new drug does not exceed the highest cost of therapy for comparable existing drugs used to treat the same disease in Canada; prices of breakthrough patented drugs and those which bring a substantial improvement are generally limited to the median of the prices charged for the same drug in other industrialized countries listed in the Regulations France, Germany, Italy, Sweden, Switzerland, U.K. and U.S. prices of most new strengths of existing medicines must bear a reasonable relationship to other strengths already on the Canadian market and rizatriptan, for example, tricor. Criqui M, Fronek A, Barret-Connor E, et al. The prevalence of peripheral arterial disease in a defined population. Circulation 1985; 71: 510-515. Meijer WT, Hoes AW, Rutgers D, et al. Peripheral arterial disease in the elderly: The Roterdam study. Arterioscler Thromb Vasc Biol 1998; 18: 185-192. Kornitzer M, Dramaix M, Sobolski J, et al. Ankle arm pressure index in asymptomatic middle-aged males: an independent predictor of ten-year coronary heart disease mortality. Angiology 1995; 46: 211-219. Newman A, Shemanski L, Manolio T, et al. Ankle-arm index as a predictor of cardiovascular disease and mortality in the cardiovascular health study. Arterioscler Thromb Vasc Biol 1999; 19: 538-545. Schroll M, Munck O. Estimation of peripheral atherosclerotic disease by ankle blood pressure measurement in a population study of 60-year old men and women. J Chron Dis 1981; 34: 261-269. Criqui MH, Denenberg JO, Bird C, et al. The epidemiology of peripheral arterial disease: importance of identifying the population at risk. Vasc Med 1997; 2: 221-226. Murabito JM, D'Agostino RB, Silbershatz H, et al. Intermittent claudication. A risk profile from the Framingham Heart Study. Circulation 1997; 96: 44-48. Jude EB, Oyibo SO, Chalmers N, et al. Peripheral arterial disease in diabetic and nondiabetic patients: A comparison of severity and outcome. Diabetes care 2001; 24: 1433-1437. Taylor LM, Jr., Moneta GL, Sexton GJ, et al. Prospective blinded study of the relationship between plasma homocysteine and progression of symptomatic peripheral arterial disease. J Vasc Surg 1999; 29: 8-19. TASC Working group. Management of peripheral arterial disease PAD ; TransAntlantic Inter-Society Consensus TASC ; . J Vasc Surg 2000; 31 1 pt 2 ; S1-S296. McGee SR, Boyko EJ. Physical examination and chronic lower-extremity ischemia: A critical review. Arch Intern Med 1998; 158: 1357-1364. Belch JJ, Topol EJ, Agnelli G, et al. Critical issues in peripheral arterial disease detection and management: a call to action. Arch Intern Med 2003; 163: 884-891. Hiatt WR. Medical treatment of peripheral arterial disease and claudication. N Eng J Med 2001; 344: 1608-1615. Hiatt WR, Hirsch AT, Regensteiner JG, et al. Clinical trials for claudication. Assessment of exercise performance, functional status and clinical end points. Vascular Clinical Trials. Circulation 1995; 92: 614-621. Heintz SE, Bone GE, Slaymaker EE, et al. Value of arterial pressure measurement in the proximal and distal part of the thigh in arterial occlusive disease. Surg Gynecol Obstet 1978; 146: 337-342. Darling RC, Raines JK, Brener BJ, et al. Quantitative segmental pulse volume recorder: A clinical tool. Surgery 1972; 72: 873-879. Kempczinski RF. Segmental volume plethysmography in the diagnosis of lower extremity arterial occlusive disease. J Cardiovasc Surg 1982; 23: 125. Olin JW, Kaufman JA, Bluemke DA, et al. Atherosclerotic vascular disease conference: Writing group IV: Imaging. Circulation 2004; 109: 2626. Koelemay MJ, den Hartog D, Prins MH, et al. Diagnosis of arterial disease of the lower extremities with duplex ultrasonography. Br J Surg 1996; 83: 404. Meijer WT, Grobbee DE, Hunink MG, et al. Determinants of peripheral arterial disease in the elderly. The Rotterdam study. Arch Intern Med 2000; 160: 2934- Jonason T, Bergstrom R. Cessation of smoking in patients with intermittent claudication. Effects on the risks of peripheral vascular complications, myocardial infarction and mortality. Acta Med Scan 1987; 221: 253-260. Skill development and efficacy mevacor online naplex determined use of antiviral and mellaril. Please see package insert for full prescribing information zocor simvastatin ; and mevacor lovastatin ; are registered trademarks of merck & co, inc lipitor atorvastatin calcium ; is a registered trademark of pfizer inc tricor fenofibrate tablets ; is a registered trademark of abbott laboratories. 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