There was no association behveen age and education, wih Chi-sq 1.4, 4 d.f, P 0.05. Over one-third of the respondents had lived in Metropolitan Toronto for fewer than ten years Table 13, III ; . Use was greatesi arnong this group 20.8% ; followed by those who had iived!
IDENTIFYING THE EFFECT OF DAYTIME SLEEPINESS ON DIABETES MANAGEMENT Chasens ER, Olshansky E School of Nursing, University of Pittsburgh, Pittsburgh, PA, USA Introduction : To achieve good glucose control, persons with type 2 diabetes mellitus T2DM ; need to engage in exercise and carefully manage their diet. Although it is known that excessive daytime sleepiness negatively affects activities sensitive to sleep disruption such as vigilance and general productivity, it is unknown how sleepiness affects diabetic management. The purpose of this study was to ask persons with T2DM to identify how daytime sleepiness affects them. Methods : This study had a qualitative design where the participants of a focus group are considered the experts in what it is like to have T2DM and be excessively sleepy. Nominal Group Technique NGT ; was used to obtain information on two questions: 1 ; what does sleepiness mean to you? and 2 ; how does daytime sleepiness affect how you deal with your diabetes? Inclusion criteria for participants was adults over age 21 with Type 2 DM, English speaking, and with a screening Epworth Sleepiness Score ESS ; 11. Two focus groups each lasting no longer than 2 hours were held. The steps to NGT include silent individual generation of ideas in writing, group recording of ideas, discussion and clarification of each idea, a preliminary vote on the priority of each idea, discussion of the preliminary vote, and a final vote on priorities. Results : A total of 12 persons participated in the two focus groups 42% male, 75% white, mean age 55.5 7.8, mean repeat ESS at focus group 11.25 3.51 ; . Significant problems identified by the participants included impaired mood and decreased motivation for engaging in health promoting activities important for diabetic management including cooking healthy meals or exercising. Conclusion : Although participants voiced they performed structured tasks such as taking their medications and testing their blood sugar, they reported that sleepiness impaired motivation to perform more complex or unstructured activities that are also important in managing T2DM. Support optional, for example, side affects.
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The authors would like to thank Medical Media Services of the Pasqua Hospital in Regina, Saskatchewan, for their help in preparation of the images. Supported by the University of Saskatchewan, College of Medicine. The authors have no financial interest in any aspect of this study.
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Many roles, including, but not limited to, temperature regulation, sensory perception and the onset of sleep. Neurons using serotonin as a transmitter are found in the brain and in the gut. A number of antidepressant drugs are targeted to brain serotonin systems. SHORT-TERM MEMORY A phase of memory in which a limited amount of information may be held for several seconds to minutes. STIMULUS An environmental event capable of being detected by sensory receptors. STROKE The third largest cause of death in America, stroke is an impeded blood supply to the brain. Stroke can be caused by a rupture of a blood vessel wall, an obstruction of blood flow caused by a clot or other material or by pressure on a blood vessel as by a tumor ; . Deprived of oxygen, which is carried by blood, nerve cells in the aected area cannot function and die. Thus, the part of the body controlled by those cells cannot function either. Stroke can result in loss of consciousness and death and
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INTRODUCTION Chemotherapy-induced vomiting The mechanisms by which chemotherapy induces vomiting are not well understood. Both peripheral gastric and intestinal ; and central stimuli may be important. Varying cytotoxic drugs can be classified as low- emetogenic Moderate emetogenic or Highly emetogenic Appendix 1 ; . Intravenous alkylating agents, doxorubicin and cisplatin typically produces nausea and vomiting 2-8hrs after infusion, and the symptoms persist for 8-36 hrs. Other drugs do not cause vomiting so frequently. After one or two cycles of chemotherapy some patients suffer from anticipatory nausea and vomiting at the sight of the nurse, doctor intravenous infusion or hospital, or even on setting out on the journey to hospital. In these patients prophylactic antiemetic therapy must be given a considerable time before chemotherapy. Several different types of drug can be used to prevent or treat vomiting. None is satisfactory in all patients and most are only partially effective. Anti-emetic therapy should be started prophalactically, and often a satisfactory regime can be established in each individual patient by trial and error. Principles of Emesis Control i ; Prevention of Nausea and vomiting is the goal. ii ; The risk of emesis and nausea last for at least 4 days for persons receiving chemotherapy of high and moderate emetogenic potential. Patients need to be protected throughout the full period of risk. iii ; Oral and IV anti-emetic formulations have equivalent effectiveness. iv ; The choice of anti-emetics used should be based on the emetogenic potential of the chemotherapy regime as well as patient risk factors. v ; There are other potential causes of emesis in cancer patients including Partial or complete bowel obstruction Vestibular dysfunction Brain metastasis Electrolyte imbalance: hypercalcaemia, hyponatraemia Uraemia Concomitant drug treatment including opiates Gastroparesis, tumour or chemotherapy vincristine etc ; Psychophysiologic: Anxiety Anticipatory nausea and vomiting and clobetasol, for example, clarinex dosage.
Paul M. Bass Chairman Charles C. Sprague, M.D. Chairman Emeritus Mrs. Kenneth Altshuler Vice Chairman W. Plack Carr Jr. President and Chief Executive Officer Donald W. Seldin, M.D. Vice President for Medical Center Relations Kay Pritchard Secretary Katy Sinor Assistant Secretary.
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| Clarinex syrup ingredientsPalliative Care Pharmacists Network 5th annual study day, 15 September, 10am to 4.30pm, Help the Hospices, London. Cost 76.38.To reserve a place contact Anne Garley on 020 7520 8208 e-mail A.Garley helpthehospices ; before 1 September.
Victim 1 B ; victim 2 C ; victim 5 D ; victim 3 E ; victims 3 and 4 8.593 4. How would you transport victim 2? A ; in the stable lateral recumbent position B ; in semi-Fowler's position C ; in the sitting position D ; in the supine recumbent position, with the lower extremities Elevated SUR-.594. Case Study A 45-year-old female patient is suspected of having colon cancer. 8.594 1. Which of the following sets of signs and symptoms is characteristic of a neoplasm of the descending colon? A ; occult bleeding; lower abdominal pain B ; constipation alternating with diarrhea, blood and mucus containing stools, abdominal cramps C ; fever; recurrent diarrhea accompanied by vomiting, colicky abdominal pain D ; recurrent tenesmus; blood and mucus containing stools; the patient complains of incomplete emptying of the rectum even by repeated attempts 8.594 2. Which of the following procedures is hazardous in mechanical intestinal obstruction due to a suspected neoplasm of the colon? A ; percussion of the abdomen B ; colonoscopy C ; a GI series of x-rays D ; rectoscopy E ; a digital rectal examination F ; a barium enema SUR-8.595. Case Study An 18-year-old female was involved in a head-on collision with another vehicle while driving her car. She was using her safety belt at the time of the accident. An 8 cm abrasion is visible in the lower region of the chest, at the level of the costal margin, slightly right to the mamillary line. Intensive care: finds the patient with pale skin and running cold sweat. Her pulse is thready; blood pressure is 100 60 mmHg. The abdomen is soft, nontender. The patient complains of pain in the right hypochondrium on breathing; the pain radiates to the right shoulder. Bradycardia is present and blood pressure falls despite parenteral volume replacement. 8.595 1. What is your tentative diagnosis? A ; contusion of the abdominal wall and cutivate.
Family of over 30 isozymes 5-6 subfamilies responsible for drug metabolism i. e., CYP3A4, CYP2D6, CYP1A2 Cause many clinically significant interactions 13 14.
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The National Heart, Lung and Blood Institute is inviting radiologists and neuroradiologists to take advantage of the MR data available through its Cardiovascular Health Study CHS ; . CHS is a longitudinal study of risk factors for development and progression of coronary heart disease and stroke in people aged 65 years and older. The CHS database includes nearly 6, 000 serial MR studies from nearly 4, 000 participants. These scans provide a robust database for the assessment of neurovascular risk factors, the influence of imaging findings on subsequent cerebrovascular or cardiovascular events, or the onset of dementia. They also provide an excellent and
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Crack Babies" Do Better When Placed with Non-Family Caregivers Ever since the epidemic of cocaine and crack use that began in the 1980s, researchers and doctors have been concerned about the development of children born to women who used cocaine during their pregnancy. Initially, research focused on the potential negative impacts of the drug itself, treating other factors associated with maternal drug use as interfering. However, as researchers accumulated more information, many concluded that focusing on the direct effect of the drug didn't provide a complete picture. In fact, in a letter to the editor of The New York Times on Nov. 28, 2003, 28 leading researchers in the field questioned whether the widely reported "crack baby" syndrome even exists. In contrast to the lack of evidence regarding the toxic nature of cocaine itself on the developing fetus, the negative effect of cocaine use on the quality of care parents provide to their young children has been consistently documented. Thus, we studied how the type of care provided to toddlers who experienced prenatal cocaine exposure affected their development. We followed 83 cocaine-exposed and 63 non-exposed children and their caregivers from birth until the children turned 2. By that age, 49 of the cocaineexposed children remained with their parents while 34 were cared for by other adults. About half of the 34 children in non-parental care were cared for by relatives kin care ; and the rest by unrelated individuals. We found that prenatal drug exposure was not directly related to the children's developmental outcome at age 2. However, we found that children in non-parental care, especially those in the care of people who were not relatives, had better environments than those cared for by their parents and performed better in several developmental areas. This improved performance existed despite the fact that these children experienced more problems at birth than the children who remained with their mothers, including prematurity, and were born to mothers who were heavier cocaine users. These results suggest that many of the negative outcomes observed in children of cocaine users may result from the quality of caregiving during infancy rather than from the direct effects of the drug in utero. If the environment is, in fact, more important in determining child developmental outcomes than prenatal cocaine exposure, then developmental problems could be prevented and treated more easily. For instance, support could be provided either through direct intervention with children, by supporting women in their recovery from substance abuse, and or in helping mothers improve their parenting skills. Finally, our study suggests that "kin" caregivers of cocaine-exposed infants and toddlers may also need support and help with parenting. Summarized from Child Development, Vol. 75, Issue 4, Prenatal Cocaine Exposure: A Comparison of Two-Year-Old Children in Parental and NonParental Care by J.V. Brown, R. Bakeman, C.D. Coles, K.A. Platzman, and and
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